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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP11 All Species: 2.42
Human Site: S56 Identified Species: 5.33
UniProt: Q8TF27 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF27 NP_597704.1 550 60549 S56 S L N N Y S S S I P L T P S T
Chimpanzee Pan troglodytes XP_001141446 439 48772
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 S284 D Y S S S V P S T P S T S Q K
Dog Lupus familis XP_848466 936 102470 A416 K K G L E S R A D S I G S G R
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 A337 K K G L E S R A D S I G S G R
Rat Rattus norvegicus Q8CGU4 1186 124419 E653 N R R G S D S E K R S L D S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZK62 781 88436 F127 F K D A K K Q F E K V S E E K
Frog Xenopus laevis Q6NRL1 864 95088 I340 L E S R A D S I G S G R A I P
Zebra Danio Brachydanio rerio XP_001921526 831 91170 A310 K K G M D G R A D S I G S G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 P430 R R S N L F I P S S S K K A D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5W7F2 827 92506 S226 V L T Y A Q Q S R E R S N Y E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75 54.9 46.7 N.A. 50.9 26.8 N.A. N.A. 23.4 47.1 47.6 N.A. 27.5 N.A. N.A. N.A.
Protein Similarity: 100 77.4 61.5 53.6 N.A. 57.5 34.7 N.A. N.A. 38.6 55.4 57.4 N.A. 37.8 N.A. N.A. N.A.
P-Site Identity: 100 0 20 6.6 N.A. 6.6 13.3 N.A. N.A. 0 6.6 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 0 33.3 20 N.A. 20 20 N.A. N.A. 20 13.3 13.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 19 0 0 28 0 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 10 19 0 0 28 0 0 0 10 0 10 % D
% Glu: 0 10 0 0 19 0 0 10 10 10 0 0 10 10 10 % E
% Phe: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 28 10 0 10 0 0 10 0 10 28 0 28 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 10 10 0 28 0 0 10 0 % I
% Lys: 28 37 0 0 10 10 0 0 10 10 0 10 10 0 19 % K
% Leu: 10 19 0 19 10 0 0 0 0 0 10 10 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 19 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 10 10 0 19 0 0 10 0 10 % P
% Gln: 0 0 0 0 0 10 19 0 0 0 0 0 0 10 0 % Q
% Arg: 10 19 10 10 0 0 28 0 10 10 10 10 0 0 37 % R
% Ser: 10 0 28 10 19 28 28 28 10 46 28 19 37 19 0 % S
% Thr: 0 0 10 0 0 0 0 0 10 0 0 19 0 0 10 % T
% Val: 10 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 10 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _